教育背景
1990 新加坡國(guó)立大學(xué)，學(xué)士（一等榮譽(yù)）
1996 英國(guó)劍橋大學(xué)，博士
工作經(jīng)歷
2008—至今 新加坡國(guó)立大學(xué),，力學(xué)生物學(xué)研究所,，首席研究員
2017—至今 新加坡國(guó)立大學(xué)，生物工程系與機(jī)械工程系,，教授
2018—至今 健康醫(yī)療創(chuàng)新與技術(shù)研究院，院長(zhǎng)
2019—至今 新加坡國(guó)立大學(xué)，生物工程系和納米科學(xué)與納米技術(shù)計(jì)劃,，創(chuàng)始董事
2021—至今 新加坡國(guó)立大學(xué)，功能智能材料研究所（I-FIM）,，首席研究員
研究方向
包括開展與人類疾病如癌癥相關(guān)的細(xì)胞力學(xué)和力學(xué)生物學(xué)方面的基礎(chǔ)研究與應(yīng)用基礎(chǔ)研究工作,，并致力于發(fā)展基于力學(xué)的微米/納米尺度的生物醫(yī)學(xué)儀器。尤其在最近, 他發(fā)明了微流體生物芯片,，用于從病人的血液中檢測(cè),、分離并恢復(fù)極少量的活體循環(huán)癌細(xì)胞，在癌癥檢測(cè),、診斷和預(yù)測(cè)方面有廣泛的應(yīng)用前景,。此項(xiàng)發(fā)明已贏得幾項(xiàng)研究成果獎(jiǎng)并已商業(yè)化。它還受到了世界范圍的廣泛關(guān)注,，并且正在各國(guó)幾家知名醫(yī)院進(jìn)行臨床測(cè)試,，也在美國(guó)和中國(guó)得到了批準(zhǔn),。
主要獎(jiǎng)項(xiàng)
1. Elected Fellow, Institution of Engineers Singapore 2023
2. Nature Lifetime Achievement Award for Mentoring in Science 2022
3. IES Prestigious Engineering Achievement Award 2022
4. Elected Fellow, International Union for Physical & Engineering Sciences in Medicine, 2022
5. Asia’s Most Influential Scientist, Fortune Times, 2021
6. Highly Cited Researcher 2018, 2019, 2021
7. IES Prestigious Engineering Achievement Award 2021, 2016, 2010
8. Elected Fellow, ASEAN Academy of Engineering and Technology 2021
9. Elected Fellow, US National Academy of Inventors 2020
10. Elected Fellow, Singapore National Academy of Science 2020
11. IP Champion, IPOS-WIPO IP Awards 2019
12. Human Frontier Science Program Research Grant Award 2012, 2018
13. Elected Fellow, ASEAN Outstanding Engineering Achievement Award 2016
14. Asian Scientist 100, 2016
15. Vladimir K. Zworykin Award, 2015
16. Elected Fellow, International Academy of Medical and Biological Engineering 2016
17. Elected Fellow, American Institute for Medical and Biological Engineering 2016
18. Elected Fellow, Academy of Engineering Singapore 2016
19. Gold, Wall Street Journal Asian Innovation Awards 2012
20. Credit Suisse Technopreneur of the Year Award 2012
21. President’s Technology Award 2011
代表性論文
已發(fā)表 470 多篇期刊出版物以及 450 多場(chǎng)特邀講座。文章總共被引用超過58,880次,，科研成就指數(shù)h-index超過122,。
1. Chen, S W, Q Zheng, Y Niu, J C Yeo, Y C Liu, J M Qi, S C Fan, X Y Liu, J Y Lee, C T Lim, Wearable flexible microfluidic sensing technologies, Nature Reviews Bioengineering, 2023.
2. Qi, J, F Gao, G Sun, J C Yeo, C T Lim, HaptGlove—Untethered Pneumatic Glove for Multimode Haptic Feedback in Reality–Virtuality Continuum, Advanced Science, 2301044, 2023.
3. Saw, T B, et al., Transepithelial potential difference governs epithelial fate by electromechanics, Nature Physics, 18, 9, 1122-1128, 2022.
4. Gaston, C, et al., EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization, Nature Communications, 12, 1, 1-22, 2021.
5. Gao, Y J, et al., A wearable multifunctional immunosensor for the monitoring of chronic wounds, Science Advances, 2021.
6. Phuong Le, A, et al., Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion, Nature Communications, 12, 397, 2021.
7. Yu, G, et al., Flexible Hybrid Sensors for Health Monitoring: Materials and Mechanisms to Render Wearability, Advanced Materials, 32, 15, 1902133, 2020.
8. Jain, S, et al., Emergence of single cell mechanical behavior and polarity within epithelial monolayers drives collective cell migration, Nature Physics, 16, 802–809, 2020.
9. Sun*, A X, et al., Potassium Channel Dysfunction in Human Neuronal Models of Angelman Syndrome, Science, 366, 1486–1492, 2019.
10. Xi, W, et al., Material Approaches to Active Tissue Mechanics, Nature Reviews Materials, 4, 23–44, 2019.
11. Ding, X, et al., Defect Engineered Bioactive Transition Metals Dichalcogenides Quantum Dots, Nature Communications, 10, 41, 2019.
12. Lim, S B, et al., Addressing Cellular Heterogeneity in Tumor and Circulation for Refined Prognostication, PNAS, 116, 17957–17962, 2019.
13. Saw, T B, et al., Biological Tissues as Active Nematic Liquid Crystals, Advanced Materials, 30, 1802579, 2018.
14. Saw, T B, et al., Topological Defects in Epithelia Govern Cell Death and Extrusion, Nature, 544, 212–216, 2017.
15. Xi, W, et al., Emergent Patterns of Collective Cell Migration under Tubular Confinement, Nature Communications, 8, 1517, 2017.
1. Lim. C T, Q M P Nguyen, Y L A Li, M Wang, N Venugopal Menon, M R G Xiong, A A Saleem Bhagat, J C Teoh, A Portable Integrated Modular System For Microfluidic Based Nucleic Acid Testing, DNA Assembly and Transformation, SG Non-Provisional Application No. 10202005023R filed on 28 May 2020.
2. W Xi, C T Lim, F Kong, X Gong, Versatile, Biocompatible Elastomeric Microtubes, European Patent Application No. 3422999 on 9 Jan 2019.
3. B L Khoo, C T Lim, G Grenci, Cell Culture, European Patent Application No. 3448986 filed on 4 Dec 2018.
4. Kenry, J C Yeo, C T Lim, A Resistive Microfluidic Pressure Sensor, US patent pub no. 2018/006700 published on 8 Mar 2018.
5. J C Yeo, W Xi, L Yu, C T Lim, Microtube Sensor for Physiological Monitoring, US Patent Application No. 62/465,002 filed on 28 Feb 2017.
6. Kenry, J C Yeo, C T Lim, Highly Wearable Flexible Liquid Graphene Oxide-Based Microfluidic Resistive Pressure Sensor, US Provisional Application Serial No. 62/137,391 filed on 24 March, 2015.
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