【講座通知】倫敦帝國理工學(xué)院Prof. Paul Langford|胸膜肺炎放線桿菌:從毒理機制到治愈方案
時間:2015年11月26日(星期四)13:30-14:30
地點:新加坡國立大學(xué)蘇州研究院創(chuàng)新中心(蘇州工業(yè)園區(qū)林泉街377號公共學(xué)院3號樓1樓)
主題:Actinobacillus pleuropneumoniae: from understanding virulence towards eradication
Prof. Paul LangfordPhD. Professor Professor of Paediatric Infectious Diseases Imperial College London
Abstract: In regard to antimicrobial resistance we have focussed on the pig pathogen A. pleuropneumoniae and developed high throughput genome wide mutagenesis protocols and screens (based on Transposon Directed Insertion site Sequencing [TraDIS]) to identify genes essential for growth in vitro and in vivo, with a view to developing novel antimicrobial and vaccine strategies. The methods developed are applicable to other pathogenic members of the Pasteurellaceae i.e. Aggregatibacter actinomycetemcomitans, H. influenzae, Mannheimia haemolytica, and P. multocida.